OUR GLP-1 WEIGHT LOSS THERAPY SERVICES

GLP-1 WEIGHT LOSS CLINIC IN MANHATTAN

Personalized Weight Loss Plans

Manhattan HRT offers a GLP-1 weight loss program designed for NYC patients seeking safe, medically supervised weight reduction using advanced GLP-1 drug medications such as Semaglutide and Tirzepatide proven for reducing weight.


 Men and women seeking Weight-Loss Injections must qualify and be eligible for treatment. If you have a BMI (Body Mass Index) of 30, or have a weight-related health condition with a BMI of 27 or more, you may be eligible for GPL-1 Weight Loss Therapy medications.


Our medical weight loss providers create personalized GLP-1 treatment plans for residents of Manhattan, Queens, Brooklyn, Long Island, and New Jersey locations.

Medically Supervised Therapy

GLP-1 Weight Loss Clinic in Manhattan, NY offering medically-supervised GLP-1 weight loss therapy using Semaglutide and Tirzepatide weight-loss drugs for men and women looking to lose weight.


Manhattan HRT is a highly rated Medical Weight​loss and Hormone Optimization clinic in NYC. We specialize in medically-supervised hormone therapy, peptide treatments, and weight loss assistance using personalized and tailored programs that address both metabolic and endocrine factors that affect body composition, age-related hormone symptoms and sexual health.


Read more about GLP-1 Weight Loss Therapy and Hormone Replacement Integration below.

Semaglutide & Tirzepatide Options

What are GLP-1 Medications? GLP-1 receptor agonists mimic a natural hormone in the body that helps regulate appetite, blood sugar, and digestion.


These medications used for medical weight loss management include:

Semaglutide (Wegovy® / Ozempic®)

Tirzepatide (Zepbound® / Mounjaro®)

Liraglutide (Saxenda®, Victoza®),  Orforglipron (Foundayo®)


Benefits include:

  • Reduced appetite
  • Dampens cravings
  • Increase fullness and satiety
  • Steady, lasting weight loss
  • Improved energy and metabolism


Which GLP-1 Drug is most effective for Medical Weight Loss?


Currently, the most effective GLP-1 drug medicine is Tirzepatide, brands Zepbound® / Mounjaro® - but Semaglutide, brands Wegovy® / Ozempic®  are very strong seconds. Both of these peptide therapies are outstanding for meaningful weight reduction.



Ongoing Support & Monitoring

Before you begin GLP-1 Weight Loss treatment, a medical screening determines your eligibility and ensures you can take these medications safety.

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How does the GLP-1 Therapy Weight Loss Program Work?

1. Comprehensive Medical Consultation. 
Your assigned medical provider reviews health history, goals, and eligibility.


2. GLP-1 Treatment Plan. Based on the assessment, a customized GLP-1 Treatment Plan is devised by your doctor determining medication type and proper dosage.


3. Medication Prescription & Delivery.

Your prescription is filled through a participating pharmacy and delivered to you.


4. Follow-up & Support. Follow-Up Visits provide evaluations to ensure that treatment and dosing are optimal. Adjustments may need to be made depending upon the results of your follow-up assessment. 

Tailored to Your Metabolism

Metabolic Effects of GLP-1 Weight Loss Therapy for clinically proven weight reduction.


  • Greater appetite control
  • Reduced food cravings
  • Minimizes emotional stress eating
  • Increases metabolism
  • Improves BMI, waist circumference, fat reduction, and overall wellness
  • Enhanced muscle tone when combined with diet and regular exercise


What to Expect?

GLP-1 treatment results vary from person to person, and even from drug to drug.  The medication will increase insulin secretion while suppressing glucagon in your body.


This will slow gastric emptying and make you feel fuller better regulating your appetite and reducing food cravings. Over 4 to 12 weeks the average weight-reduction is 3% to 6% and over 12 to 18 months, a 15% to 22.5% reduction in weight is possible.


What is the Dosage?

Semaglutide dosage is typically 0.25 mg, 0.5 mg, 1.7 mg, 2.4 mg, or 7.2 mg taken weekly.


Tirzepatide dosage is typlically 2.5 mg weekly, 5 mg, 7.5 mg, 10mg, 12.5 mg and can go as high as 15 mg weekly.


Liraglutide dosage is typically 0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg and 3 mg taken once daily.


Administration? Given by weekly (or daily) by either pill (oral GLP-1) or subcutaneous self-injection depending on the medication and medical guidance you receive.


Possible GLP-1 Side Effects? Temporary nausea, fullness, or GI discomfort which can be alleviated by either adjusting dosage or other recommendation made by your provider.


How Long to See Results?  Typically, patients see steady progress over 4–12 weeks. However, full treatment effects are seen over 12 to 18 months.


Support & Monitoring? Follow-up appointments for treatment evaluation and dose adjustments.


Weight Loss Program Customization?
Every GLP-1 Therapy Plan is tailored to your medical history, health goals, safety and comfort.


Hormone & Peptide Integration

Manhattan HRT offers integrated Peptide Therapy and Hormone Replacement Therapy protocols. This provides a holistic approach to wellness and healthy aging by seamlessly integrating GLP-1 peptide therapy with bioidentical hormone replacement therapy.


This powerful combination not only aids in weight loss through appetite regulation but also complements testosterone, estrogen, and other hormone treatments to enhance overall balance and health.


Our expert hormone specialists are dedicated to helping you regain vitality, balance, and sex drive whether you're managing menopause or andropause, seeking effective sexual health solutions, or pursuing advanced anti-aging therapies.


Bio-Identical Hormone Treatment programs available include TRT (Testosterone Replacement Therapy), Estrogen & Progesterone Therapy, Oxytocin Therapy,
ED Therapies for Men  & FSD (HSDD) Treatments for Women, Thyroid Treatment, HGH (Human Growth Hormone) and Sermorelin Peptide Therapy under close medical supervision.


Contact us to experience the benefits of personalized care personalized and tailored just for you.

Our patients have achieved meaningful weight loss through personalized GLP-1 treatments, combining Semaglutide and Tirzepatide with expert medical guidance and ongoing support tailored to their unique metabolic needs.

Client Success Stories with GLP-1 Therapy

GLP-1 Weight Loss Program Ratings

After starting the GLP-1 program at Manhattan HRT,
I have lost about 26 pounds in six months. The personalized approach helped me manage hunger and cravings, improved my energy levels. I have lost 2 dress sizes and am very happy to say the least.

Patricia M.,
Manhattan, NY

GLP-1 Weight Loss Clinic Reviews

The doctor’s attention to my hormone balance alongside GLP-1 therapy made a big difference. I have more energy and have started back in the gym twice a week. The weight loss is noticeable. I am down a full pant's size.

David G.,
Brooklyn, NY

GLP-1 Therpay Review

Combining GLP-1 injections with hormone optimization has allowed me to lose weight more quickly. I don't feel as hungry all the time as I used to so the GLP-1 medication really works. The medical supervision helped to guide me and keep me on track.

Melinda H.,
Queens, NY

GLP-1 Therapy FAQs

Our GLP-1 therapy program combines Semaglutide and Tirzepatide treatments tailored to your metabolic profile. We provide personalized assessments and continuous medical support to help you achieve long-term weight loss while addressing hormonal balance and overall health.

  • What is GLP-1 therapy?

    GLP-1 therapy uses medications like Semaglutide and Tirzepatide to regulate appetite and improve blood sugar control. These drugs mimic natural hormones that influence metabolism, helping reduce hunger and promote fat loss under medical supervision.

  • How effective is GLP-1 for weight loss?

    Clinical studies show significant weight reduction with GLP-1 treatments when combined with lifestyle and dietary changes. Patients often experience improved energy levels and metabolic health alongside gradual, consistent fat loss. Over a 12 month period some patients have experienced a 15% to 20% reduction in body weight although this is not always achievable. Diet and exercise also play a big role.

  • Is GLP-1 therapy safe?

    GLP-1 medications are FDA-approved and administered under medical supervision at our clinic. We monitor your progress closely to minimize side effects and adjust treatment to your individual needs. Both glucon-like peptide-1 (GLP-1) receptor agonists and glucose-dependent insulinotropic polypeptides (GIP/GLP-1) receptor agonists have been clinically tested and proven for weight-loss.

  • How does GLP-1 fit into a healthy lifestyle?

    GLP-1 therapy complements balanced nutrition, sleep, and regular exercise. It supports appetite control and metabolic function, making it easier to maintain healthy eating habits and long-term weight management.

  • Who is a good candidate for GLP-1 therapy?

    Men and women struggling with weight related obesity, excessive BMI, metabolic or hormonal imbalances and other weight-related health conditions may benefit. Our medical team evaluates your health history and goals to design a personalized GLP-1  weigh-loss treatment plan.

  • How much do GLP-1 drugs cost?

    • Semaglutide Injectables (Wegovy & Ozempic), can range from $199 to $349 per month depending on the dose. The pill form is approximately $149 per month.
    • Tirzeptide Injectables like the Zepbound KwikPen (Zepbound & Mounjaro), can range from $299 per month to $449 per month depending on the dose.
    • Orforglipron (Foundayo) $149 per month to $299 per month.
    • Liraglutide (Saxenda) about $375  for the generic.

Patient Experiences

Clients report improved weight control and enhanced well-being after starting GLP-1 therapy. Our tailored approach ensures each patient receives ongoing guidance and adjustments to maximize results. In addition to metabolic effects and improved blood sugar control, glucagon-like peptide-1 receptor agonists (GLP-1R) can have positive cardiovascular effects, anti-inflammatory effects, and reduce blood pressure and stroke risk.

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Start Your GLP-1 Weight Loss Journey Today

Our GLP-1 therapy combines Semaglutide and Tirzepatide treatments tailored to your metabolic needs. With personalized assessments and continuous medical support, we help you achieve lasting weight loss while addressing hormonal balance and overall health.

Take Control of Your Health Now

Connect with our Manhattan GLP-1 Weight Loss clinic to discuss your weight loss goals and hormone optimization options. Our HRT team is ready to guide you through a customized plan designed for lasting results, increased energy, and improved well-being.

Connect with Manhattan Hormone Replacement Therapy

Located in the heart of Manhattan, our clinic offers personalized GLP-1 weight loss therapy with Semaglutide and Tirzepatide. Reach out via our contact form or follow us on social media for expert guidance and ongoing support tailored to your health goals.

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